Skip to main content

Table 2 Correlation of rheumatoid arthritis characteristics and B-cell subset distributions a

From: High levels of memory B cells are associated with response to a first tumor necrosis factor inhibitor in patients with rheumatoid arthritis in a longitudinal prospective study

  Lymphocytes (%) B cells (%)
Characteristics CD19+ CD27+ CD27+IgD+ CD27+IgD- CD27-IgD+ CD27-IgD-
RA duration, yr -0.23b -0.11 -0.10 -0.13 0.07 0.08
Steroid dose, mg/day -0.06 0.25c 0.20 0.27c -0.23b 0.16
TNFi agents used (n) -0.16 -0.15 -0.07 -0.17 0.16 -0.21b
DAS28 score 0.03 0.10c 0.18c 0.02 -0.10 -0.04c
  1. aDAS28, Disease Activity Score in 28 joints; Ig, Immunoglobulin; RA, Rheumatoid arthritis; TNFi, Tumor necrosis factor inhibitor. bP < 0.05, cP < 0.01. cCorrelations were not significant; however CD27+, CD27+IgD+ and CD27-IgD- proportions were higher in patients with active RA than in those with low disease activity after adjustment for age, sex and steroid dose (general linear models). Data are Spearman’s r statistics.