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Table 2 Correlation of rheumatoid arthritis characteristics and B-cell subset distributions a

From: High levels of memory B cells are associated with response to a first tumor necrosis factor inhibitor in patients with rheumatoid arthritis in a longitudinal prospective study

 

Lymphocytes (%)

B cells (%)

Characteristics

CD19+

CD27+

CD27+IgD+

CD27+IgD-

CD27-IgD+

CD27-IgD-

RA duration, yr

-0.23b

-0.11

-0.10

-0.13

0.07

0.08

Steroid dose, mg/day

-0.06

0.25c

0.20

0.27c

-0.23b

0.16

TNFi agents used (n)

-0.16

-0.15

-0.07

-0.17

0.16

-0.21b

DAS28 score

0.03

0.10c

0.18c

0.02

-0.10

-0.04c

  1. aDAS28, Disease Activity Score in 28 joints; Ig, Immunoglobulin; RA, Rheumatoid arthritis; TNFi, Tumor necrosis factor inhibitor. bP < 0.05, cP < 0.01. cCorrelations were not significant; however CD27+, CD27+IgD+ and CD27-IgD- proportions were higher in patients with active RA than in those with low disease activity after adjustment for age, sex and steroid dose (general linear models). Data are Spearman’s r statistics.