Table 1 Summary of cytokine secretion by Mo and MoDC
Cytokines (pg/ml) | Control; median (IQR) | LPS + IFN-γ; median (IQR) | LPS + IFN-γ + ABP; median (IQR) | P |
|---|---|---|---|---|
Mo IL-12 | 0 (0; 0) | 1 (0; 10) | 0 (0; 0) | 0.0159 |
Mo IL-10 | 0 (0; 5) | 205 (110; 340) | 328 (206; 369) | ns |
Mo TNFα | 0 (0; 6) | 617 (302; 912) | 147 (82: 195) | 0.0005 |
Mo IL-1β | 0 (0; 4) | 448 (232; 953) | 261 (155; 688) | 0.0186 |
Mo IL-6 | 175 (57; 403) | 10,059 (5,074; 13,251) | 11,682 (7,537; 17,425) | ns |
Mo IL-23 | 115 (99; 181) | 277 (188; 521) | 184 (137; 244) | 0.036 |
MoDC IL-12 | 0 (0; 0) | 45 (9; 166) | 0 (0; 5) | 0.0038 |
MoDC IL-10 | 0 (0; 0) | 117 (53; 176) | 228 (157; 260) | 0.001 |
MoDC TNFα | 0 (0; 5) | 458 (374; 786) | 241 (145, 481) | 0.0033 |
MoDC IL-1β | 0 (0; 0) | 0 (0; 0) | 0 (0, 8) | ns |
MoDC IL-6 | 13 (0; 29) | 10,255 (7,262, 12,864) | 8,131 (5,160; 11,310) | ns |
MoDC IL-23 | 130 (41; 152) | 172 (104; 386) | 134 (93; 249) | ns |