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Table 4 Multivariate analyses indicating contribution of 14-3-3η to total variance in radiographic damage status and radiographic progression a

From: 14-3-3η is a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage

Cohort

Outcome

 

Without 14-3-3η

With 14-3-3η

≥0.2 ng/ml

≥0.4 ng/ml

≥0.8 ng/ml

Early RA

Joint damage status

Model LR

2.99

7.06

8.54

8.54

p

0.084

0.029

0.014

0.014

R 2

0.065

0.154

0.187

0.187

Radiographic progression

Model LR

11.16

12.27

13.72

13.72

P

0.004

0.007

0.003

0.003

R 2

0.252

0.273

0.310

0.310

Established RA

Joint damage status

Model LR

12.35

13.94

12.36

12.76

P

0.006

0.008

0.015

0.013

R 2

0.376

0.425

0.377

0.389

Radiographic progression

Model LR

8.78

9.71

13.78

13.13

P

0.003

0.008

0.001

0.001

R 2

0.167

0.185

0.262

0.250

  1. aLR, Likelihood ratio; RA, Rheumatoid arthritis.