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Table 4 Multivariate analyses indicating contribution of 14-3-3η to total variance in radiographic damage status and radiographic progression a

From: 14-3-3η is a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage

Cohort Outcome   Without 14-3-3η With 14-3-3η
≥0.2 ng/ml ≥0.4 ng/ml ≥0.8 ng/ml
Early RA Joint damage status Model LR 2.99 7.06 8.54 8.54
p 0.084 0.029 0.014 0.014
R 2 0.065 0.154 0.187 0.187
Radiographic progression Model LR 11.16 12.27 13.72 13.72
P 0.004 0.007 0.003 0.003
R 2 0.252 0.273 0.310 0.310
Established RA Joint damage status Model LR 12.35 13.94 12.36 12.76
P 0.006 0.008 0.015 0.013
R 2 0.376 0.425 0.377 0.389
Radiographic progression Model LR 8.78 9.71 13.78 13.13
P 0.003 0.008 0.001 0.001
R 2 0.167 0.185 0.262 0.250
  1. aLR, Likelihood ratio; RA, Rheumatoid arthritis.