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Table 3 Future research requirements for the most promising non-classification laboratory assays

From: Antiphospholipid syndrome in 2014: more clinical manifestations, novel pathogenic players and emerging biomarkers

Test Assay Future research needs
Anti-DI antibodies ELISA Analytical and post-analytical standardization
CIA Retrospective and prospective clinical validation
Anti-PS/PT antibodies ELISA Analytical and post-analytical standardization
Retrospective confirmatory studies and prospective clinical validation
Anti-PE antibodies ELISA Analytical and post-analytical standardization
Retrospective confirmatory studies and prospective clinical validation
Annexin A5 resistance assay Two-step coagulation assay Analytical and post-analytical standardization
   Retrospective and prospective clinical validation
  1. CIA, chemiluminescence immunoassay; DI, domain I; ELISA, enzyme-linked immunosorbent assay; PE, phosphatidylethanolamine; PS/PT, phosphatidylserine-prothrombin.
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Arthritis Research & Therapy

ISSN: 1478-6362

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