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Table 3 Comparison of disease activity and organ involvement among AAV diseases

From: Classification and characteristics of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis in a nationwide, prospective, inception cohort study

  EGPA GPA MPA/RLV Unclassifiable
(n = 14) (n = 33) (n = 78) (n = 31)
BVAS 16.1 ± 7.7 19.9 ± 7.4 18.4 ± 7.3 12.1 ± 7.6
General 10 (71.4) 23 (69.7) 56 (71.8) 29 (93.6)
Cutaneousa,b 10 (71.4) 3 (9.1) 16 (20.5) 10 (32.3)
Mucous membranes/eyes 1 (7.1) 8 (24.2) 9 (11.5) 2 (6.5)
Ear, nose, and throata,b,c 6 (42.9) 28 (84.9) 7 (9.0) 1 (3.2)
Chestc 5 (35.7) 22 (66.7) 30 (38.5) 6 (19.4)
Cardiovascular 2 (14.3) 4 (12.1) 6 (7.7) 0 (0)
Abdominal 0 (0) 1 (3.0) 0 (0) 1(3.2)
Renala,b 2 (14.3) 21 (63.6) 71 (91.0) 15 (48.4)
Nervous systema,b 13 (92.9) 14 (42.4) 33 (42.3) 15 (48.4)
  1. Values expressed as mean ± standard error or number (percentage). Disease activity and patterns of organ involvement were defined by the BVAS 2003 scoring system. AAV, antineutrophil cytoplasmic antibody-associated vasculitis; BVAS, Birmingham Vasculitis Activity Score; EGPA, eosinophilic granulomatosis with polyangiitis; GPA, granulomatosis with polyangiitis (Wegener’s granulomatosis); MPA, microscopic polyangiitis; RLV, renal-limited vasculitis. Comparisons between the EGPA, GPA, and MPV/RLV groups were made by Student t test or Mann–Whitney U test. Statistical significance was determined by P < 0.05/3 using Bonferroni correction: aEGPA versus GPA, bEGPA versus MPA/RLV, cGPA versus MPA/RLV. Unclassifiable AAV was not compared with other forms of AAV.