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Table 2 Recent-onset rheumatoid arthritis patients in the Sherbrooke Early Undifferentiated PolyArthritis Cohort a

From: Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels

Patient demographics (N= 339) Seronegative Seropositive
Number of patients (%) 166 (49%) 173 (51%)
Average age, yr (range) 54.2 (21 to 92) 65.6 (19 to 87)
Females, n (%) 107 (64) 105 (61)
Symptom duration, yr 0.44 0.45
SE status, n 120 132
  SE alleles = 0 75 43
  SE alleles = 1 44 59
  SE alleles = 2 1 30
Mean DAS28-CRP (±SD) 5.10 (1.47) 5.04 (1.44)
Mean CRP mg/L (±SD) 24.4 (33.9) 26.6 (35.6)
Mean Sharp score erosions (±SD) 2.9 (6.1) 3.8 (7.0)
Mean Sharp score narrowing (±SD) 3.4 (6.1) 2.2 (4.1)
Tender joints 10.4 9.8
Swollen joints 10.5 10.2
Patient VAS score (100-mm scale) 54.2 53.9
  1. aCRP, C-reactive protein; DAS28-CRP, Disease Activity Score in 28 joints C-reactive protein; SE, Shared epitope; VAS, Visual Analogue Scale. Seronegative vs seropositive analysis: Symptom duration, P = 0.85; DAS28-CRP, P = 0.72; CRP, P = 0.56; Sharp score erosions, P = 0.28; Sharp score narrowing, P = 0.09.