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Table 1 Clinical characteristics of the study cohorts

From: Genetic variant in IL33 is associated with susceptibility to rheumatoid arthritis

  Discovery population Validation population Replication population
Number of cases 700 586 666
Ethnicity Northern Han Chinese Southern Han Chinese Northern and Southern
Female, % 79.9 81.2 82.8
Age, mean ± SD years 54.0 ± 13.1 52.4 ± 13.9 54.3 ± 12.8
Age at RA onset, mean ± SD years 46.4 ± 16.0 46.3 ± 15.0 46.6 ± 15.4
Disease duration, mean ± SD years 8.1 ± 8.1 7.8 ± 7.3 9.0 ± 10.3
ACPA status, % positive 72.6 75.3 68.9
RF status, % positive 81.6 78.3 84.0
  1. ACPA, anti-citrullinated proteins antibodies; RF, rheumatoid factor.