Imaging/mediator | CF
max
| RAMRIS synovitis | RAMRIS BME | RAMRIS erosion |
---|
|
P-value (approximate ρ) |
P-value (approximate ρ) |
P-value (approximate ρ) |
P-value (approximate ρ) |
---|
MCP-1
| 0.009 (0.41) | 0.17 (0.48) | 0.01 (0.42) | 0.03 (0.31) |
IL-6
| 0.23 (0.22) | 0.04 (0.50) | 0.04 (0.25) | 0.03 (0.35) |
IL-8
| 0.09 (0.27) | 0.08 (0.58) | 0.16 (0.27) | 0.07 (0.43) |
MIP-1β
| 0.02 (0.38) | 0.02 (0.63) | 0.95 (0.35) | 0.62 (0.30) |
-
aCFmax, Maximal systolic colour fraction; BME, Bone marrow oedema; IL, Interleukin; MCP-1, Monocyte chemoattractant protein 1; MIP-1, Macrophage inflammatory protein 1β; RAMRIS, Rheumatoid arthritis magnetic resonance imaging score.
- A mixed model has been used for the statistical analysis: P < 0.05 was considered significant. In the reduced model, covariates were excluded if P > 0.10. This table contains the data from the reduced models. The full models including stepwise covariate elimination steps and model optimization transformation can be found in the supplementary files.
- The pre-specified covariates included in the statistical model: Joint Synovectomized = Wrist, MCP or PIP; Synovectomy position = Ulnar, central, radial, or mixed for pooled synovectomy positions; Side = left or right;
- Approx. rho = approximated Spearman’s rho; RAMRIS BME = RAMRIS bone marrow edema component; RAMRIS Erosion = RAMRIS erosion score component; RAMRIS synovitis = RAMRIS synovitis score component; IL-6 = Interleukin 6; IL-8 = Interleukin 8, MCP-1 = Monocyte chemoattractant protein 1; MIP-1b = Macrophage Inflammatory Protein 1 beta.