|
Imaging/mediator
|
CF
max
|
RAMRIS synovitis
|
RAMRIS BME
|
RAMRIS erosion
|
|---|
| |
P-value (approximate ρ)
|
P-value (approximate ρ)
|
P-value (approximate ρ)
|
P-value (approximate ρ)
|
|---|
|
MCP-1
|
0.009 (0.41)
|
0.17 (0.48)
|
0.01 (0.42)
|
0.03 (0.31)
|
|
IL-6
|
0.23 (0.22)
|
0.04 (0.50)
|
0.04 (0.25)
|
0.03 (0.35)
|
|
IL-8
|
0.09 (0.27)
|
0.08 (0.58)
|
0.16 (0.27)
|
0.07 (0.43)
|
|
MIP-1β
|
0.02 (0.38)
|
0.02 (0.63)
|
0.95 (0.35)
|
0.62 (0.30)
|
-
aCFmax, Maximal systolic colour fraction; BME, Bone marrow oedema; IL, Interleukin; MCP-1, Monocyte chemoattractant protein 1; MIP-1, Macrophage inflammatory protein 1β; RAMRIS, Rheumatoid arthritis magnetic resonance imaging score.
- A mixed model has been used for the statistical analysis: P < 0.05 was considered significant. In the reduced model, covariates were excluded if P > 0.10. This table contains the data from the reduced models. The full models including stepwise covariate elimination steps and model optimization transformation can be found in the supplementary files.
- The pre-specified covariates included in the statistical model: Joint Synovectomized = Wrist, MCP or PIP; Synovectomy position = Ulnar, central, radial, or mixed for pooled synovectomy positions; Side = left or right;
- Approx. rho = approximated Spearman’s rho; RAMRIS BME = RAMRIS bone marrow edema component; RAMRIS Erosion = RAMRIS erosion score component; RAMRIS synovitis = RAMRIS synovitis score component; IL-6 = Interleukin 6; IL-8 = Interleukin 8, MCP-1 = Monocyte chemoattractant protein 1; MIP-1b = Macrophage Inflammatory Protein 1 beta.
