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Table 1 Characteristics for each data-set

From: A genetic variant in osteoprotegerin is associated with progression of joint destruction in rheumatoid arthritis

Cohort

Leiden-EAC

Groningen

Sheffield

Lund

 

(n = 600)

(n = 275)

(n = 391)

(n = 147)

Year of diagnosis

1993-2006

1945-2001

1938-2003

1985-1990

Follow-up years*

7 years

14 years

Not applicable*

5 years

Total no. of X-ray sets

2,846

862

391

781

Method of scoring

SHS

SHS

Larsen

Larsen

Female n (%)

412 (69)

194 (71)

290 (73)

98 (67)

Age at diagnosis, mean ± SD

56 ± 16

49 ± 13

46 ± 13

51 ± 12

ACPA + n (%)

323 (55)

160 (80)

302 (79)

114 (80)

Rheumatoid factor n (%)

343 (59)

258 (94)

N/A*

115 (81)

  1. SHS Sharp-van der Heijde score.
  2. *Data of Leiden-EAC, Groningen and Lund were from baseline onwards during respectively 7, 14 and 5 years of follow-up. The data of Sheffield were collected once during the disease period, the mean disease duration was 15 years (range 3–65 years).
  3. N/A not available.