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Table 1 Characteristics for each data-set

From: A genetic variant in osteoprotegerin is associated with progression of joint destruction in rheumatoid arthritis

Cohort Leiden-EAC Groningen Sheffield Lund
  (n = 600) (n = 275) (n = 391) (n = 147)
Year of diagnosis 1993-2006 1945-2001 1938-2003 1985-1990
Follow-up years* 7 years 14 years Not applicable* 5 years
Total no. of X-ray sets 2,846 862 391 781
Method of scoring SHS SHS Larsen Larsen
Female n (%) 412 (69) 194 (71) 290 (73) 98 (67)
Age at diagnosis, mean ± SD 56 ± 16 49 ± 13 46 ± 13 51 ± 12
ACPA + n (%) 323 (55) 160 (80) 302 (79) 114 (80)
Rheumatoid factor n (%) 343 (59) 258 (94) N/A* 115 (81)
  1. SHS Sharp-van der Heijde score.
  2. *Data of Leiden-EAC, Groningen and Lund were from baseline onwards during respectively 7, 14 and 5 years of follow-up. The data of Sheffield were collected once during the disease period, the mean disease duration was 15 years (range 3–65 years).
  3. N/A not available.