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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases

Figure 4

Phagocytosis of sRBC iC3b by CR3-expressing COS-7cells as measured with the Phagocytic Index. Phagocytic Index, mean number of internal sRBCiC3b/100 COS-7 cells. F941V significantly impairs phagocytosis (P = 0.002). No significant difference observed between WT and either common polymorphism M441T (P = 0.74) and A858V (P = 0.92), or the rare variant G1145S (P = 0.37).

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Arthritis Research & Therapy

ISSN: 1478-6362

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