Expression of B-cell subsets in IgG4-related disease (RD), primary Sjögren’s syndrome (pSS), and healthy controls (HC). Representative flow cytometry pictures of different B-cell subsets from HC, IgG4-RD, and pSS patients (A). The percentages of CD19+ B cells out of total lymphocytes in each group (B). Percentages of Breg cells, mature B cells, and memory B cells out of total B cells in each group (C, D, E). Summary of different B-cell subsets in different populations (F). Percentages of CD19 + CD24-CD38hi B cells out of total B cells in each group (G). Values are shown as mean ± standard error of the mean, *P <0.05, **P <0.01, ***P <0.001.