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Table 1 Clinical and laboratory findings in IgG4-related disease, primary Sjögren’s syndrome and healthy controls

From: B cell subsets and dysfunction of regulatory B cells in IgG4-related diseases and primary Sjögren’s syndrome: the similarities and differences

 

Healthy controls

IgG4-related disease

Primary Sjögren’s syndrome

Number

30

48

38

Gender, male/female, n

7/23

29/19

3/35

Age, years

46.4 ± 10.0

53.17 ± 13.66***

42.2 ± 9.6

Disease duration, months

NA

29.45 ± 41.35*

51.32 ± 47.6

ESR, mm/h

NA

49.35 ± 33.80**

30.68 ± 28.35

C-reactive protein, mg/L

NA

9.17 ± 3.67**

2.65 ± 1.64

Immunoglobulin (Ig)G, g/L

10.11 ± 1.47

24.58 ± 10.74

22.99 ± 11.48

IgA, g/L

2.28 ± 0.74

1.85 ± 0.76***

4.17 ± 2.23

IgM, g/L

1.02 ± 0.50

0.82 ± 0.38**

1.24 ± 0.64

IgG1, mg/dL

797.83 ± 106.54

1036.55 ± 670.09**

1485.74 ± 486.36

IgG2, mg/dL

554.6 ± 228.80

592.76 ± 396.55**

372.95 ± 126.70

IgG3, mg/dL

41.68 ± 22.10

78.61 ± 64.05

60.03 ± 41.41

IgG4, mg/dL

57.06 ± 46.06

1929.10 ± 1923.63***

36.45 ± 37.74

IgG4/total IgG% 1

3.90 ± 3.10

39.03 ± 25.84***

1.86 ± 1.85

  1. Values are shown as mean ± SD unless stated otherwise. 1IgG level is the sum of IgG1, IgG2, IgG3 and IgG4. ***P <0.001; **P <0.01; *P <0.05 (compared with Primary Sjögren’s syndrome). ESR, erythrocyte sedimentation rate; NA, not applicable.
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Arthritis Research & Therapy

ISSN: 1478-6362

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