| |
Healthy controls
|
IgG4-RD
|
pSS
|
IgG4-related disease versus HC
|
pSS versus HC
|
IgG4-RD versus pSS
|
|---|
|
P-value
|
P-value
|
P-value
|
|---|
|
CD19+ (%)1
|
4.41 ± 1.75
|
6.43 ± 2.73
|
8.97 ± 4.40
|
0.001
|
<0.001
|
0.009
|
|
CD19 + CD24 + CD38- (%)2
|
14.01 ± 10.39
|
22.71 ± 12.81
|
15.79 ± 10.58
|
0.002
|
0.541
|
0.009
|
|
CD19 + CD24intCD38int (%)2
|
53.70 ± 15.12
|
36.68 ± 14.27
|
49.75 ± 11.59
|
<0.001
|
0.150
|
<0.001
|
|
CD19 + CD24hiCD38hi (%)2
|
3.98 ± 2.70
|
2.17 ± 3.96
|
12.55 ± 5.15
|
<0.001
|
<0.001
|
<0.001
|
|
CD19 + CD24-CD38hi (%)2
|
2.16 ± 1.65
|
6.99 ± 6.24
|
2.39 ± 2.64
|
<0.001
|
0.868
|
<0.001
|
|
CD19 + CD40+ (%)2
|
87.08 ± 11.27
|
44.35 ± 21.79
|
69.48 ± 20.33
|
<0.001
|
<0.001
|
<0.001
|
|
CD19 + BAFF-R + (%)2
|
94.13 ± 3.50
|
76.63 ± 20.85
|
88.96 ± 8.90
|
0.001
|
0.005
|
0.066
|
|
CD19 + CD80+ (%)2
|
17.54 ± 7.41
|
43.27 ± 8.64
|
23.69 ± 14.24
|
<0.001
|
0.327
|
0.037
|
|
CD19 + CD86+ (%)2
|
19.56 ± 7.70
|
47.18 ± 14.23
|
27.45 ± 12.17
|
0.002
|
0.325
|
0.041
|
- Values are shown as mean ± SD. 1Percentages of CD19+ cells in total lymphocytes. 2Percentages of B cell subsets in CD19+ cells. IgG4-RD, IgG4-related disease; pSS, primary Sjögren’s syndrome.
