Figure 2From: Intrinsic multipotential mesenchymal stromal cell activity in gelatinous Heberden’s nodes in osteoarthritis at clinical presentation Multipotential stromal cell (MSC) differentiation and immunophenotyping. (A) Representative images show trilineage differentiation capacity of Heberden’s node (HN)-MSCs compared with synovial fluid (SF)- and iliac crest bone marrow (ICBM)-MSCs. Adipogenesis of HN-MSC was low, and only micro-vesicles were observed (insert). (B) Plot showing mean percentage of populations positive for cell surface markers by flow cytometry (n = 3 for HN-, SF- and ICBM-MSCs). Error bars represent standard deviation. Below are example histogram overlays of Heberden’s node (blue), synovial fluid (green), and bone marrow (red) MSCs with isotype control (grey-filled).Back to article page