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Table 1 Demographics and patient population characteristics versus healthy blood donors

From: Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility

 

Controls

RA

Statistics

Age

50.34 ± 1.5

53.03 ± 1.5

P = 0.214

Gender (F/M)

24/32

24/8

-

DAS28

n.a.

3.07 ± 1.12

-

Bone erosion (pos/neg)

n.a.

22/10

-

Serum ACPA (pos/neg)

n.a.

20/12

-

Serum RF (pos/neg)

n.a.

19/13

-

Serum ANA (pos/neg)

n.a.

21/11

-

ESR (mm/h)

n.a.

16.8 ± 13.1

-

CRP (mg/L)

n.d.

6.9 ± 5.2

-

PBMC (cells/μl)

1,961 ± 81.69

1513 ± 75.90

P < 0.0001

PMN (cells/μl)

3,641 ± 149.7

4575 ± 546.0

P = 0.021

Therapy (yes/no)

n.a.

31/1

-

DMARDs (yes/no)

n.u.

27/5

-

Biologics (yes/no)

n.a.

30/2

-

  1. F, female; M, male; DAS28, disease activity score; n.a., not applicable; pos, positive; neg, negative; ACPA: anti-citrullinated protein antibodies; RF, rheumatoid factor; ANA, antinuclear antibody; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; n.d., not determined; PBMC, peripheral blood mononuclear cell; PMN, polymorphonuclear leukocyte; DMARD, disease-modifying antirheumatic drug; n.u., not used.
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Arthritis Research & Therapy

ISSN: 1478-6362

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