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Table 2 Associations of C-reactive protein with muscle strength change in patients with knee osteoarthritis

From: Elevated C-reactive protein is associated with lower increase in knee muscle strength in patients with knee osteoarthritis: a 2-year follow-up study in the Amsterdam Osteoarthritis (AMS-OA) cohort

Independent factors Muscle strength change, N-m/kg
  β P value
CRP (crude)   
 Not elevated at baseline and at follow-up Ref.  
 Elevated at baseline and not elevated at follow-up 0.05 0.51
 Not elevated at baseline and elevated at follow-up -0.09 0.22
 Elevated at both times of assessment -0.17 0.02
CRPa,b
 Not elevated at baseline and at follow-up Ref.  
 Elevated at baseline and not elevated at follow-up 0.06 0.38
 Not elevated at baseline and elevated at follow-up -0.06 0.38
 Elevated at both times of assessment -0.17 0.02
CRPa-c
 Not elevated at baseline and at follow-up Ref.  
 Elevated at baseline and not elevated at follow-up 0.06 0.44
 Not elevated at baseline and elevated at follow-up -0.06 0.42
 Elevated at both times of assessment -0.16 0.03
CRPa-d
 Not elevated at baseline and at follow-up Ref.  
 Elevated at baseline and not elevated at follow-up 0.03 0.71
 Not elevated at baseline and elevated at follow-up -0.07 0.38
 Elevated at both times of assessment -0.18 0.02
CRPa-e
 Not elevated at baseline and at follow-up Ref.  
 Elevated at baseline and not elevated at follow-up 0.01 0.92
 Not elevated at baseline and elevated at follow-up -0.09 0.25
 Elevated at both times of assessment -0.20 0.01
CRPa-f
 Not elevated at baseline and at follow-up Ref.  
 Elevated at baseline and not elevated at follow-up 0.01 0.90
 Not elevated at baseline and elevated at follow-up -0.09 0.26
 Elevated at both times of assessment -0.19 0.01
CRPa-g   
 Not elevated at baseline and at follow-up Ref.  
 Elevated at baseline and not elevated at follow-up 0.01 0.93
 Not elevated at baseline and elevated at follow-up -0.09 0.25
 Elevated at both times of assessment -0.19 0.01
CRPa-h   
 Not elevated at baseline and at follow-up Ref.  
 Elevated at baseline and not elevated at follow-up 0.05 0.57
 Not elevated at baseline and elevated at follow-up -0.09 0.25
 Elevated at both times of assessment -0.21 0.01
  1. This linear regression analysis used muscle strength change as a dependent factor. All of the models were adjusted for baseline muscle strength. Additionally, confounders adjusting the model were aage, bgender, ccomorbidities change, dnon-steroidal anti-inflammatory drug change, ebody mass index change, fWestern Ontario and McMaster Universities Osteoarthritis pain change, gKellgren-Lawrence score change, and hphysical activity follow-up. Reduce patient numbers in the multivariate linear regression analyses due to random missing in the outcome measure or selected predictors. CRP, C-reactive protein; Ref., reference.