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Table 1 Clinical and demographic characteristics of study cohorts at start of follow-up a

From: The risk of acute coronary syndrome in rheumatoid arthritis in relation to tumour necrosis factor inhibitors and the risk in the general population: a national cohort study

Clinical and demographic characteristics RA patients starting TNFi (N = 7,704) Biologic-naïve RA referents (N = 23,112) General population referents (N=38,520)
Female sex 5,845 (76) 17,535 (76) 29,225 (76)
Age, mean ± SD (yr) 57.1 ± 12.1 57.3 ± 12.2 57.2 ± 12.2
RA duration >10 yr 1,509 (19.6) 3,864 (16.7)  
Comorbidity, previous diagnosis    
  Diabetes 379 (4.9) 1,251 (5.4) 1,342 (3.5)
  Hypertension 833 (10.8) 2,689 (11.6) 2,571 (6.7)
  Chronic obstructive pulmonary disease 196 (2.5) 653 (2.8) 450 (1.2)
  Cerebrovascular disease 177 (2.3) 696 (3.0) 938 (2.4)
  Other atherosclerotic diseaseb 505 (6.6) 1,803 (7.8) 1,774 (4.6)
  Infections (hospitalization) 1,675 (21.7) 5,287 (22.9) 5,487 (14.2)
Number of days in hospital within 10 years before inclusion, median (IQR) 4 (0 to 17) 3 (0 to 14) 0 (0 to 5)
Previous joint surgeryc 1,974 (25.6) 4,669 (20.2) 1,392 (3.6)
Education level attained    
  ≤9 years or less 2,197 (28.5) 7,062 (30.6) 10,303 (26.8)
  10 to 12 years 3,494 (45.4) 10,473 (45.3) 16,796 (43.6)
  >12 years 1,983 (25.7) 5,455 (23.6) 11,182 (29.0)
Any disability pension in year before inclusiond 2,601 (33.8) 7,195 (31.1) 4,993 (13.0)
Sick leave the year before inclusione    
During part of year (14 to 349 days) 2,091 (27.1) 5,075 (22.0) 4,319 (11.2)
  Whole year (≥350 days) 240 (3.1) 596 (2.6) 386 (1.0)
  1. aRA, Rheumatoid arthritis; TNFi, Tumour necrosis factor inhibitor. Values are number of patients (%) unless otherwise stated. b‘Other atherosclerotic disease’ includes arterial occlusion and stenosis of cerebral and precerebral arteries, transient ischaemic attack, cerebral atherosclerosis, late effects of cerebrovascular disease, atherosclerosis, aortic aneurysm, other aneurysm or dissection, peripheral arterial disease, arterial embolism or thrombosis, and atherosclerosis with gangrene. c‘Previous joint surgery’ includes knee prosthesis, hip prosthesis, shoulder prosthesis, foot surgery and hand surgery. d‘Disability pension’ is 25% to 100% of any period of time during the year before inclusion. eThe registered number of days on sick leave also includes work-free days for any sick leave longer than 5 days. Periods of sick leave lasting 14 days or less are not included in the Statistics Sweden database.