Table 3 Multivariate analysis of covariate effects on the modified Rodnan skin score in a subsample of women with early disease (n = 370)
From: Effect of menopause on the modified Rodnan skin score in systemic sclerosis
Covariate | Multivariate effect estimate (95% CI) |
|---|---|
Menopausal status | |
Premenopausal | Reference |
Postmenopausal | −3.36 (−5.87, −0.85) |
Disease subtype | |
Diffuse | Reference |
Limited | −13.50 (−16.10, −10.99) |
Menopause*disease typeb | 1.91 (−0.83, 4.65) |
Time since baseline (years) | −0.13 (−0.40, 0.14) |
Disease duration at baseline (years) | −0.47 (−0.98, 0.04) |
Age at disease onset (years) | 0.04 (0.00, 0.08) |
Race/ethnicity | |
White | Reference |
Black | −0.64 (−2.85, 1.11) |
Other | −0.87 (−1.42, 0.50) |
Smoking | |
Never | Reference |
Ever | 0.86 (−0.55, 2.15) |
Oral contraceptive pill | |
Past/never | Reference |
Current | −0.78 (−2.15, 0.43) |
Hormone replacement therapy | |
Past/never | Reference |
Current | 0.08 (−2.84, 3.00) |
DMARDsc | |
Past/never | Reference |
Current | 0.10 (−1.61, 1.81) |
Cyclophosphamide | |
Never | Reference |
Ever | −0.33 (−2.31, 1.65) |