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Table 2 Odds ratio for the association of antibody-positive patients within the different HLA-DRB1 groups

From: Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice

  No SE (n = 47) HLA-DRB1*01 (n = 50) HLA-DRB1*04 (n = 127)
Antigen Frequency of positive patients (%) Frequency of positive patients (%) Odds ratio DR*01 vs. no SE Frequency of positive patients (%) Odds ratio DR*04 vs. no SE Odds ratio DR*04 vs. DR*01
C1 sera 14.9 16 1.088, 95% CI 0.3613 to 0.280 11.8 0.7653, 95% CI0.291 to 2.013 0.703, 95% CI 0.278 to 1.780
C1 SF 10.6 22 2.369, 95% CI 0.755 to 7.436 25.2 2.829, 95% CI 1.030 to 7.771 1.194, 95% CI 0.547 to 2.605
J1 sera 6.4 14 2.388, 95% CI 0.579 to 9.845 5.5 0.856, 95% CI 0.212 to 3.457 0.3583, 95% CI 0.119 to 1.081
J1 SF 6.4 8 1.275, 95% CI 0.361 to 3.280 7.1 1.119, 95% CI 0.289 to 4.324 0.469, 95% CI 0.164 to 1.336
U1 sera 42.6 38 0.827, 95% CI 0.367 to 1.865 48 1.227, 95% CI 0.624 to 2.413 1.483, 95% CI 0.759 to 2.898
U1 SF 68.1 82 2.135, 95% CI 0.828 to 5.506 76.4 1.516, 95% CI 0.7245 to 3.169 0.710, 95% CI 0.310 to 1.627
CitC1 sera 27.6 26 0.919, 95% CI 0.374 to 2.258 53 2.921, 95% CI 1.410 to 6.049 3.178, 95% CI 1.544 to 6.541
CitC1 SF 17 26 1.713, 95% CI 0.637 to 4.606 48.8 4.650, 95% CI 2.014 to 10.74 2.715, 95% CI 1.319 to 5.586
  1. CI, confidence interval; SF, synovial fluid.