Low-dose oral imatinib in the treatment of systemic sclerosis interstitial lung disease unresponsive to cyclophosphamide: a phase II pilot study

Table 1 Baseline demographic, clinical and immunological features of the study population

Male/female	9 (30%)/21 (70%)
Age (years)	51 (41.75 to 62)
Disease duration (years)	3 (1 to 6)
Anti-DNA topoisomerase I/anti-centromere antibodies	28 (93.3%)/1 (3.3%)
Systemic sclerosis, lcSSc/dcSSc	14 (46%)/16 (53.3%)
Pulmonary function tests
FVC% predicted	76.5 (63.23 to 89.30)
TLC% predicted	75 (65 to 86)
DLco% predicted	43 (37 to 54)
High-resolution computed tomography
Ground-glass	10 (6 to 13.75)
Honeycombing	10.5 (6.25 to 16.25)
Modified Rodnan skin score	10.5 (5.25 to 20)
Health Assessment Questionnaire	0.375 (0 to 1)

Data presented as number of patients (%) or median (25th to 75th percentile). dcSSc, diffuse cutaneous systemic sclerosis; DLco, diffusion lung capacity of carbon monoxide; FVC, forced vital capacity; lcSSc, limited cutaneous systemic sclerosis; TLC, total lung capacity.

ISSN: 1478-6362