Skip to main content

Table 2 Biologic processes in which genes associated with differential expression during monocyte-to-macrophage differentiation

From: Inflammatory expression profiles in monocyte-to-macrophage differentiation in patients with systemic lupus erythematosus and relationship with atherosclerosis

Biological process

Genes in PANTHER database

Observed

Expected

χ2p value

Immune system process

2,628

127

52.93

9.98 × 10-22

Signal transduction

4,191

147

84.41

5.75 × 10-13

Apoptosis

966

45

19.45

2.18 × 10-7

B cell-mediated immunity

314

21

6.32

2.49 × 10-6

Lipid metabolic process

1,119

46

22.54

4.59 × 10-6

Intracellular signaling

1,568

58

31.58

6.08 × 10-6

Macrophage activation

305

19

6.14

1.97 × 10-5

Response to interferon-gamma

105

10

2.11

6.83 × 10-5

Induction of apoptosis

358

19

7.21

1.58 × 10-4

Carbohydrate metabolism

952

35

19.17

5.33 × 10-4

Complement activation

162

11

3.26

5.43 × 10-4

  1. PANTHER, Protein Analysis Through Evolutionary Relationships.