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Table 1 Participant characteristics

From: The clinical significance, natural history and predictors of bone marrow lesion change over eight years

  BML present (n = 127) BML not present (n = 71) P value
Females (%) 41% (51/127) 47% (33/71) 0.4
Age (years) 47.6 (6.5) 47.2 (6.0) 0.65
Offspring (%) 58% (74/127) 49% (35/71) 0.22
BMI (kg/m2) 28.0 (5.8) 27.0 (4.2) 0.24
Height (cm) 168.5 (9.2) 169.1 (8.9) 0.7
Weight (kg) 79.6 (18.1) 77.6 (15.1) 0.43
Leg strength (kg) 114.9 (47.4) 118.3 (44.3) 0.64
Active smokers (%) 17.3 15.5 0.77
Light activity (per unit change) 4.1 (0.09) 4.00 (0.15) 0.43
Strenuous activity (per unit change) 2.65 (0.12) 2.52 (0.15) 0.51
Radiographic osteoarthritis (%) 20% (26/127) 10 (7/71) 0.06
Pain score (0 to 29) 3.7 (5.9) 1.3 (3.1) <0.01
Change in pain score (-25 to 44) 2.5 (8.1) 2.2 (4.2) 0.84
Total BML area (0 to 4.10 cm2) 0.63 (0.80)
MF BML area (0 to 1.98 cm2) 0.37 (0.50)
LF BML area (0 to 2.54 cm2) 0.64 (0.75)
MT BML area (0 to 1.83 cm2) 0.33 (0.36)
LT BML area (0 to 1.99 cm2) 0.26 (0.31)
SP BML area (0 to 1.70 cm2) 0.38 (0.34)
IP BML area (0 to 1.06 cm2) 0.23 (0.27)
Change in BML area (-2.09 to 4.46 cm2) 0.61 (1.03) 0.28 (0.46) 0.01
  1. Values were taken from visit two of the study, except for radiographic osteoarthritis that was taken from visit one. Change refers to the difference in values between visit two and visit three. Values represent mean (standard deviation) unless percentages. Light and strenuous activity were rated on a five-point scale: 1 = no days, 2 = 1 or 2 days, 3 = 3 to 5 days, 4 = 6 to 8 days, and 5 = 9 days or more spent doing at least 20 minutes of the respective level of activity in the past 14 days. BMI, body mass index; BML, bone marrow lesion; IP, inferior patella; LF, lateral femoral; LT, lateral tibial; MF, medial femoral; MT, medial tibial; SP, superior patella. Bold data indicate P <0.05.