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Table 3 Relationship between change in WOMAC and site-specific change in BML size

From: The clinical significance, natural history and predictors of bone marrow lesion change over eight years

  Univariable Multivariablea
Medial tibial 2.96 (0.59, 5.34) 3.67 (0.89, 6.45)
 Controls -1.39 (-4.18, 1.40) -3.38 (-7.15, 0.39)
 Offspring 8.99 (5.30, 12.68) 8.98 (5.22, 12.73)
Lateral tibial 2.37 (0.08, 4.66) 1.98 (-0.36, 4.32)
Medial femoral 2.11 (-1.14,5.36) 1.63 (-1.64, 4.90)
Lateral femoral -0.09 (-2.41, 2.24) -0.69 (-3.11, 1.73)
Superior patella 0.74 (-2.73, 4.21) 0.61 (-2.85, 4.08)
Inferior patella 3.95 (-0.59, 8.50) 4.30 (-0.26, 8.86)
  1. Data presented as beta coefficient (95% confidence interval). Values are the change in WOMAC pain score per cm2 change in BML size. An interaction between offspring and control status was present at the medial tibial site (P <0.01). BML, bone marrow lesion; WOMAC, Western Ontario and McMasters Universities Arthritis Index. Bold data indicate P <0.05. aAdjusted for age, sex, body mass index, leg strength, and radiographic osteoarthritis.