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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Naproxen affects osteogenesis of human mesenchymal stem cells via regulation of Indian hedgehog signaling molecules

Figure 5

The effect of the Hedgehog (HH) signaling pathway inhibitor cyclopamine (Cpn) on the expression of COL10A1 (A), ALP (B), OPN (C) and COL1A1 (D) in mesenchymal stem cells (MSCs) cultured in osteogenic differentiation medium with 0.5 μM naproxen (Npx) for 6 and 12 days. The results are shown as mean ± SD of three independent experiments with MSCs from three different donors. *P <0.05; **P <0.01 cells cultured with both cyclopamine (Cpn) and naproxen (Npx) versus cells cultured with Npx only.

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Arthritis Research & Therapy

ISSN: 1478-6362

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