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Table 2 Adalimumab and antiadalimumab antibody levels in serum of rheumatoid arthritis patients a

From: Adalimumab regulates intracellular TNFα production in patients with rheumatoid arthritis

Patient Adalimumab levels (mg/ml) Antiadalimumab levels (AU/ml) Discontinuation cause
4 wk 12 wk 24 wk 4 wk 12 wk 24 wk
1 n.d. n.d. n.d. n.d. n.d. n.d.
2 n.d. n.d. n.d. n.d. n.d. n.d.
3 n.d. n.d. 9.62 n.d. n.d. NG
4 n.d. n.d. 10.06 n.d. n.d. NG
5 n.d. n.d. 4.9 n.d. n.d. NG
6 n.d. n.d. 14.697 n.d. n.d. NG
8 14 14.4 24.065 NG NG NG
9 n.d. n.d. 39.409 n.d. n.d. NG
10 n.d. n.d. n.d. n.d. n.d. n.d.
12 n.d. n.d. 8 n.d. n.d. NG
7 7.8 7 NG NG NG NG Allergy
11 NG NG NG 297,268 81,833 2,925 Lack of efficacy
  1. an.d., Not determined; NG, Negative.