Table 2 Adalimumab and antiadalimumab antibody levels in serum of rheumatoid arthritis patients a
From: Adalimumab regulates intracellular TNFα production in patients with rheumatoid arthritis
Patient | Adalimumab levels (mg/ml) | Antiadalimumab levels (AU/ml) | Discontinuation cause | ||||
|---|---|---|---|---|---|---|---|
4 wk | 12 wk | 24 wk | 4 wk | 12 wk | 24 wk | ||
1 | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | – |
2 | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | – |
3 | n.d. | n.d. | 9.62 | n.d. | n.d. | NG | – |
4 | n.d. | n.d. | 10.06 | n.d. | n.d. | NG | – |
5 | n.d. | n.d. | 4.9 | n.d. | n.d. | NG | – |
6 | n.d. | n.d. | 14.697 | n.d. | n.d. | NG | – |
8 | 14 | 14.4 | 24.065 | NG | NG | NG | – |
9 | n.d. | n.d. | 39.409 | n.d. | n.d. | NG | – |
10 | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | – |
12 | n.d. | n.d. | 8 | n.d. | n.d. | NG | – |
7 | 7.8 | 7 | NG | NG | NG | NG | Allergy |
11 | NG | NG | NG | 297,268 | 81,833 | 2,925 | Lack of efficacy |