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Figure 1 | Arthritis Research & Therapy

Figure 1

From: 18 F-Fluoride positron emission tomography/computed tomography for noninvasive in vivo quantification of pathophysiological bone metabolism in experimental murine arthritis

Figure 1

Joint inflammation in glucose-6-phosphate isomerase–induced arthritis. (A) Photographs showing inflammation in fore- and hindpaws of arthritic mice (two at right) and nonimmunized control animals (two at left). (B) Clinical course of inflammatory arthritis in DBA/1 mice (n = 7). GPI, Glucose-6-phosphate isomerase induction. (C) Arthritis was associated with destruction of bone. Shown is a representative image of metatarsal bone revealing cortical bone lesions (arrows) and infiltration of immune cells to the sites of inflammation. B, Bone; BM, Bone marrow; J, Joint; CI, Cellular infiltrate; MT, Metatarsal. Original magnification = 20× (left) and 200× (right).

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Arthritis Research & Therapy

ISSN: 1478-6362

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