Discriminant validity, responsiveness and reliability of the arthritis-specific Work Productivity Survey assessing workplace and household productivity within and outside the home in patients with axial spondyloarthritis, including nonradiographic axial spondyloarthritis and ankylosing spondylitis

Osterhaus, Jane T; Purcaru, Oana

doi:10.1186/ar4680

Table 5 Work Productivity Survey baseline scores by defined known groups: household productivity and daily activities (randomized set, observed cases) ^a

From: Discriminant validity, responsiveness and reliability of the arthritis-specific Work Productivity Survey assessing workplace and household productivity within and outside the home in patients with axial spondyloarthritis, including nonradiographic axial spondyloarthritis and ankylosing spondylitis

Instrument^b	Number of days of household work missed over the previous month, mean		Number of days with household productivity ≤50% at work over the previous month, mean		Number of days of missed family, social, or leisure activities over the previous month, mean		Number of days with outside help over the previous month, mean		Rate of arthritis interference with household work productivity over previous month, mean^c
	Worse	Better	Worse	Better	Worse	Better	Worse	Better	Worse	Better
BASDAI
axSpA (cutoff 5.30 and 7.60)	9.36^d	3.28	9.38^e	5.44	6.05^d	2.47	2.21^f	0.78	6.00^d	3.83
axSpA (cutoff 5.30 and 7.60)	n = 84	n = 86	n = 84	n = 86	n = 84	n = 86	n = 84	n = 86	n = 84	n = 86
AS (cutoff 5.20 and 7.60)	8.96^d	3.04	8.39^f	5.28	6.07^d	2.30	1.72^f	0.53	5.96^d	3.77
AS (cutoff 5.20 and 7.60)	n = 46	n = 47	n = 46	n = 47	n = 46	n = 47	n = 46	n = 47	n = 46	n = 47
nr-axSpA (cutoff 5.40 and 7.60)	9.84^d	3.38	10.58^f	5.82	6.03^e	2.51	2.82	1.08	6.05^d	3.62
nr-axSpA (cutoff 5.40 and 7.60)	n = 38	n = 39	n = 38	n = 39	n = 38	n = 39	n = 38	n = 39	n = 38	n = 39
BASFI
axSpA (cutoff 3.80 and 7.00)	9.90^d	2.95	9.24^f	6.38	6.91^d	2.71	3.01^e	0.90	6.17^d	3.56
axSpA (cutoff 3.80 and 7.00)	n = 87	n = 84	n = 87	n = 84	n = 87	n = 84	n = 87	n = 84	n = 87	n = 84
AS (cutoff 4.40 and 7.10)	10.66^d	1.93	9.98^d	4.56	6.68^d	2.07	2.49^d	0.38	6.45^d	3.56
AS (cutoff 4.40 and 7.10)	n = 47	n = 45	n = 47	n = 45	n = 47	n = 45	n = 47	n = 45	n = 47	n = 45
nr-axSpA (cutoff 3.00 and 6.80)	9.13^f	4.03	9.34	7.51	7.66^e	2.78	3.53	1.70	6.16^d	3.54
nr-axSpA (cutoff 3.00 and 6.80)	n = 38	n = 37	n = 38	n = 37	n = 38	n = 37	n = 38	n = 37	n = 38	n = 37
Total Spine Pain
axSpA (cutoff 6 and 8)	8.35^d	2.54	8.51^d	4.83	5.89^d	3.03	2.06	1.78	6.09^d	3.61
axSpA (cutoff 6 and 8)	n = 136	n = 109	n = 136	n = 109	n = 136	n = 109	n = 136	n = 109	n = 136	n = 109
AS (cutoff 6 and 8)	7.68^d	2.36	8.03^e	3.91	5.14^d	1.54	1.42	1.45	6.00^d	3.71
AS (cutoff 6 and 8)	n = 76	n = 56	n = 76	n = 56	n = 76	n = 56	n = 76	n = 56	n = 76	n = 56
nr-axSpA (cutoff 6 and 8)	9.20^d	2.74	9.13^f	5.81	6.83	4.60	2.87	2.13	6.20^d	3.51
nr-axSpA (cutoff 6 and 8)	n = 60	n = 53	n = 60	n = 53	n = 60	n = 53	n = 60	n = 53	n = 60	n = 53
SF-36 PCS
axSpA (cutoff 37.35 and 27.30)	9.73^d	2.23	10.85^d	3.81	6.45^d	2.13	3.23^d	0.38	6.25^d	3.28
axSpA (cutoff 37.35 and 27.30)	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80
AS (cutoff 36.49 and 26.73)	9.55^d	1.89	11.43^d	4.30	5.61^e	2.00	1.39	0.45	6.32^d	3.43
AS (cutoff 36.49 and 26.73)	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44
nr-axSpA (cutoff 38.25 and 27.40)	9.17^d	2.61	9.72^d	3.25	7.42^e	2.28	5.11^d	0.44	5.81^d	3.00
nr-axSpA (cutoff 38.25 and 27.40)	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36
SF-36 MCS
axSpA (cutoff 49.39 and 30.79)	8.88^d	5.40	10.83^e	6.69	8.63^d	1.74	4.03^e	1.28	5.94^d	4.30
axSpA (cutoff 49.39 and 30.79)	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80	n = 80
AS (cutoff 49.93 and 31.38)	8.45^f	4.61	10.25^f	6.43	7.41^d	1.30	2.52	1.00	6.14^e	4.52
AS (cutoff 49.93 and 31.38)	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44	n = 44
nr-axSpA (cutoff 48.41 and 30.18)	10.36	6.36	11.64^f	6.56	10.00^d	2.28	5.39^f	1.53	5.92^f	4.19
nr-axSpA (cutoff 48.41 and 30.18)	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36	n = 36
ASQoL
axSpA (cutoff 9.00 and 15.00)	10.13^d	2.66	10.41^d	4.59	8.43^d	1.29	4.21^d	0.97	6.75^d	3.32
axSpA (cutoff 9.00 and 15.00)	n = 97	n = 90	n = 97	n = 90	n = 97	n = 90	n = 97	n = 90	n = 97	n = 90
AS (cutoff 9.00 and 15.00)	9.00^d	2.30	10.49^d	4.30	6.96^d	1.43	3.30^d	0.55	6.42^d	3.47
AS (cutoff 9.00 and 15.00)	n = 53	n = 47	n = 53	n = 47	n = 53	n = 47	n = 53	n = 47	n = 53	n = 47
nr-axSpA (cutoff 9.00 and 15.00)	11.50^d	3.05	10.32^e	4.91	10.20^d	1.14	5.30^f	1.42	7.16^d	3.16
	n = 44	n = 43	n = 44	n = 43	n = 44	n = 43	n = 44	n = 43	n = 44	n = 43

^aASQoL: Ankylosing spondylitis quality of life; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; MCS: Mental Components Summary; PCS: Physical Components Summary; SF-36: Short form 36 items. ^bCutoff points represent the first and third quartiles of baseline scores: “Worse” state is defined for each individual measure as BASDAI score at or above the third quartile; BASFI score at or above the third quartile; Total Back Pain score at or above the third quartile; ASQoL at or above the third quartile; SF-36 MCS at or below the first quartile; SF-36 PCS at or below the first quartile; “better” state is defined for each individual measure as BASDAI score at or below the first quartile; BASFI score at or below the first quartile; Total Back Pain score at or below the first quartile; ASQoL score at or below the first quartile; SF-36 MCS, PCS at or above the third quartile. ^cWPS Q4 is scored on a 0 to 10 scale, where 0 = no interference and 10 = complete interference. ^dP ≤ 0.001; ^eP ≤ 0.01; ^fP ≤ 0.05; nonparametric bootstrap-t method with a variance stabilizing transformation, 10,000 replications.

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