Skip to main content

Table 2 Comparison of cytokines secreted by immature or TLR7/8 stimulated mature moDC from pSS patients and controls analyzed by multiplex Luminex analyses

From: Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren’s syndrome

Cytokine (pg/ml) Patients immature (n = 21) Controls immature (n = 17) Patients mature (n = 20) Controls mature (n = 16)
IL-7 30.9 ± 11.0 35.3 ± 29.8 31.4 ± 11.0 40.3 ± 16.2*
IL-12p40 703.9 ± 878.8 498.9 ± 362.8 3847.9 ± 5867.8 796.3 ± 326.8**
IL-17 86.0 ± 22.1 83.2 ± 31.9 76.6 ± 15.1 101.5 ± 39.4*
TNFα 28.9 ± 22.1 24.3 ± 8.8 53.9 ± 20.5 39.8 ± 17.9*
Interferon gamma 18.3 ± 7.9 24.1 ± 12.5 20.5 ± 8.9 29.1 ± 9.3**
MIP-1α 298.5 ± 138.8 304.3 ± 146.5 398.7 ± 201.3 304.6 ± 228.5*
  1. Only cytokines with a significant different value are shown. Data presented as mean ± standard deviation. IL, interleukin; MIP, macrophage inflammatory protein; moDC, monocyte-derived dendritic cells; pSS, primary Sjögren’s syndrome; TLR, toll-like receptor; TNFα, tumor necrosis factor alpha. A significant difference (*P < 0.05 and **P < 0.01) for the levels of six different cytokines was found when comparing mature moDC from pSS patients with mature moDC from healthy controls.