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Figure 3 | Arthritis Research & Therapy

Figure 3

From: How does infliximab work in rheumatoid arthritis?

Figure 3

Effect of infliximab on circulating IL-1ra in patients treated with a single infusion of infliximab or placebo on Day 0. Infliximab 1 mg/kg (closed triangle ▲), infliximab 10 mg/kg (closed square ■), and placebo (open circle ). *P < 0.05, **P < 0.01, ***P < 0.001 compared with placebo. Adapted with permission from Charles et al. [19]. Copyright 1999. The American Association of Immunologists.

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