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Table 1 Levels of IL-12p40 and IL-12p70 in synovial fluid (SF) and sera from patients with rheumatoid arthritis

From: Regulation of CD154-induced interleukin-12 production in synovial fluid macrophages

 

Cytokine concentration (pg/ml)a

 

IL-12p70

IL-12p40

Patient no.

SF

Serum

SF

Serum

1

124

<8

314

82

2

388

8,040

1,238

19,305

3

<8

88

<31

<31

4

316

56

552

250

5

<8

<8

<31

180

6

3,770

240

2,790

818

7

154

146

646

886

8

<8

<8

<31

<31

9

354

400

772

1,266

10

<8

<8

<31

<31

11

56

<8

638

142

12

110

190

694

976

13

258

450

958

1,708

14

<8

<8

<31

<31

15

<8

<8

<31

<31

16

<8

<8

<31

<31

17

132

844

334

2,026

18

<8

150

<31

574

19

76

40

228

<31

20

335

1,030

1,976

3,274

21

<8

<8

86

<31

22

<8

<8

<31

<31

23

<8

<8

<31

<31

24

<8

<8

88

<31

25

<8

<8

<31

<31

26

<8

1,260

<31

2,400

27

<8

870

<31

1,740

28

<8

<8

<31

<31

29

318

3,580

744

8,260

30

3,400

15,300

7,860

80,100

31

<8

<8

<31

<31

32

90

156

526

946

33

2,985

1,240

4,380

1,896

34

<8

119

<31

846

35

<8

2,000

<31

29,160

Mean ± SEM

372 ± 160

1,038 ± 489

724 ± 259

4,502 ± 2,431

  1. aCytokine concentrations were determined using cytokine specific ELISAs. Each value is a mean of duplicate determinations. Limit values were used for levels under detection limits.