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Table 3 Anti-TNF therapy in ankylosing spondylitis – open questions

From: Therapy of ankylosing spondylitis and other spondyloarthritides: established medical treatment, anti-TNF-α therapy and other novel approaches

Long-term efficacy?

Arrest of progression of ankylosis?

Differing responses in different targets?

Dosage?

Intervals?

Continous or intermittent therapy?

Individualization of treatment?

Long-term safety?

Repeated screening for autoantibodies?

Adding of DMARDs to suppress antibody formation?

Duration of tuberculosis prophylaxis?

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Arthritis Research & Therapy

ISSN: 1478-6362

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