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Table 1 The most-studied components of cartilage matrix

From: The role of structural genes in the pathogenesis of osteoarthritic disorders

Collagens
   Types IIa and IIb
   Type III
   Type VI
   Type IX
   Type X
   Type XI
   Type XII
   Type XIV
Proteoglycans
   Aggrecan
   Versican
   Link protein
   Biglycan (DS-PGI)
   Decorin (DS-PGII)
   Epiphycan (DS-PGIII)
   Fibromodulin
   Lumican
   Perlecan
   Proteoglycan 4
Noncollagenous proteins
   COMP (cartilage oligomeric matrix protein; thrombospondin-5)
   CMP (cartilage matrix protein; matrilin-1)
   Matrilin-3
   CILP (cartilage intermediate layer protein)
   Fibronectin
   PRELP (proline/arginine-rich and leucine-rich repeat protein)
   Chondroadherin
   Fibrillin
   Tenascin-C
   Elastin
   MGP (matrix Gla protein)
   Chondromodulin-I
   Chondromodulin-II
   CD-RAP (cartilage-derived retinoic acid-sensitive protein)
   ANKH
   Matrix metalloproteinases and related enxymes
   Tissue inhibitors of metalloproteinases