Skip to main content

Table 1 Clinical characteristics of systemic sclerosis (SSc) patients, patients with pre-SSc and healthy controls

From: Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers

Characteristic SSc (n = 43) Pre-SSc (n = 9) Healthy (n = 21)
Age (years), median (range) 61 (24–79) 58 (32–70) 55 (29–96)
Gender    
   Male 8/43 0/9 5/21
   Female 35/43 9/9 16/21
Disease subset    
   Diffuse 23/43 -  
   Limited 20/43 -  
Disease phase    
   Early 25/43 -  
   Intermediate/late 18/43 -  
Fingertip ulcers    
   Positive 16/43 -  
   Negative 27/43 -  
Other skin ulcers    
   Positive 18/43 -  
   Negative 25/43 -  
Skin score    
   Diffuse SSc, median (range) 22 (4–45) -  
   Limited SSc, median (range) 11 (4–30) -  
Capillaroscopy    
   Early 6/43 1/9  
   Active 22/43 7/9  
   Late 14/43 0/9  
   No changes 1/43 1/9  
Autoantibodies    
   Antinuclear antibody-positive 39/43 9/9  
   Anti-Scl-70 autoantibody-positive 13/43 0/9  
   Anticentromere antibody-positive 11/43 7/9  
   No autoantibodies 4/43 0/9  
Carbon monoxide diffusion capacity (%), median (range) 70 (26–144) -  
  1. See text for definitions.