Table 1 Clinical characteristics of systemic sclerosis (SSc) patients, patients with pre-SSc and healthy controls
Characteristic | SSc (n = 43) | Pre-SSc (n = 9) | Healthy (n = 21) |
|---|---|---|---|
Age (years), median (range) | 61 (24–79) | 58 (32–70) | 55 (29–96) |
Gender | |||
Male | 8/43 | 0/9 | 5/21 |
Female | 35/43 | 9/9 | 16/21 |
Disease subset | |||
Diffuse | 23/43 | - | |
Limited | 20/43 | - | |
Disease phase | |||
Early | 25/43 | - | |
Intermediate/late | 18/43 | - | |
Fingertip ulcers | |||
Positive | 16/43 | - | |
Negative | 27/43 | - | |
Other skin ulcers | |||
Positive | 18/43 | - | |
Negative | 25/43 | - | |
Skin score | |||
Diffuse SSc, median (range) | 22 (4–45) | - | |
Limited SSc, median (range) | 11 (4–30) | - | |
Capillaroscopy | |||
Early | 6/43 | 1/9 | |
Active | 22/43 | 7/9 | |
Late | 14/43 | 0/9 | |
No changes | 1/43 | 1/9 | |
Autoantibodies | |||
Antinuclear antibody-positive | 39/43 | 9/9 | |
Anti-Scl-70 autoantibody-positive | 13/43 | 0/9 | |
Anticentromere antibody-positive | 11/43 | 7/9 | |
No autoantibodies | 4/43 | 0/9 | |
Carbon monoxide diffusion capacity (%), median (range) | 70 (26–144) | - |