TY - JOUR AU - van Holten, Judith AU - Plater-Zyberk, Christine AU - Tak, Paul P. PY - 2002 DA - 2002/09/18 TI - Interferon-β for treatment of rheumatoid arthritis? JO - Arthritis Research & Therapy SP - 346 VL - 4 IS - 6 AB - IFN-β treatment is emerging as a potentially effective form of therapy in various immune-mediated conditions. The present review addresses the possible role of IFN-β in immune-mediated diseases such as multiple sclerosis and rheumatoid arthritis. Several placebo-controlled trials are discussed, as are the available immunological data that are relevant to this field. Review of these data provides evidence that IFN-β has some beneficial therapeutic effect in patients with relapsing-remitting multiple sclerosis and might also have antirheumatic potential. This notion is supported by recent studies showing a critical role for IFN-β in bone homeostasis. SN - 1478-6362 UR - https://doi.org/10.1186/ar598 DO - 10.1186/ar598 ID - van Holten2002 ER -