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Arthritis Research & Therapy
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Table 1
Ex vivo
and
in vivo
gene transfer to the synovial lining of rabbits' knee joints
*
From:
Lessons learned from gene transfer approaches
In vivo
Ex vivo
Level of expression
High
Low-medium
Duration of expression
~ 2 weeks
Up to 6 weeks
Transduced cells
Types A+B synoviocytes
Type B synoviocytes
Various leukocytes
Laboriousness
Low
High
Inflammatory response
Present
Absent
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