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Figure 2 | Arthritis Res Ther

Figure 2

From: The relationship between predicted peptide–MHC class II affinity and T-cell activation in a HLA-DRβ1*0401 transgenic mouse model

Figure 2

Dose-dependent proliferative response to predicted DR4 binding peptides in DR4-IE transgenic mice. DR4-IE transgenic mice were immunized with the indicated peptides and 10 days later their lymph node cells (4 × 105) were challenged in vitro with the same peptide. Data represents the average proliferative response ± SEM of three mice for each peptide tested. This is representative of three independent experiments with similar results. CII, type II collagen; hAG, human aggrecan; HBsAg, hepatitis B surface antigen.

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