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Figure 5 | Arthritis Res Ther

Figure 5

From: A novel mechanism for the regulation of IFN-γ inducible protein-10 expression in rheumatoid arthritis

Figure 5

Representative photomicrographs showing the immunohistochemical localization of antigenic IFN-γ inducible protein-10 (IP-10) within interacting leukocytes and fibroblast-like synoviocytes (FLSs). After 24 hours of incubation, the cells were labeled with anti-IP-10 antibodies. Rheumatoid arthritis FLSs plus (A and B) monocytes or (C and D) polymorphonuclear neutrophils. Panels A and C, stained by control IgG; panels B and D, stained by anti-IP-10 antibody. Panels B and D demonstrate a significant presence of cell-associated IP-10 antigen (arrows) in leukocytes. (Original magnification: 500×.)

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