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Figure 1 | Arthritis Res Ther

Figure 1

From: Decreased effector memory CD45RA+ CD62L- CD8+ T cells and increased central memory CD45RA- CD62L+ CD8+ T cells in peripheral blood of rheumatoid arthritis patients

Figure 1

Naïve and memory CD4+ and CD8+ T-cell subpopulations in patients with rheumatoid arthritis (RA), patients with systemic lupus erythematosus (SLE), and healthy control individuals. (a) Representative flow cytometry showing naïve and memory subpopulations of CD4+ and CD8+ T cells from one RA patient and a sex- and age-matched control individual. (b) Pooled data showing naïve and memory subpopulations of CD4+ and CD8+ T cells from RA patients (n = 8) and control individuals (n = 8). Horizontal lines indicate means. (c) Pooled data showing naïve and memory subpopulations of CD4+ and CD8+ T cells from SLE patients (n = 12) and control individuals (n = 12). Horizontal lines indicate means. (d) The correlation between age and CD45RA+CD62L- terminally differentiated CD8+ T cells from control individuals (n = 13), RA patients (n = 8), and SLE patients (n = 12) is shown. The P values were calculated using Mann–Whitney U test and Student's t-test for panel b and linear regression for panel d.

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