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Table 1 Specific COX-2 inhibitors in patients with aspirin-exacerbated respiratory disorders (aspirin-induced asthma)

From: COX-2: Where are we in 2003? - Specific cyclooxygenase-2 inhibitors and aspirin-exacerbated respiratory disease

Study

COX-2 inhibitor

Number of patients

Adverse reaction*

Aspirin response

Woessner et al. [3]

Celecoxib

60

No

Yes

Dahlen et al. [9]

Celecoxib

27

No

Not tested

Szczeklik et al. [8]

Rofecoxib

12

No

Yes

Stevenson et al. [10]

Rofecoxib

60

No

Yes

  1. * Decrease in FEV1 (forced expiratory volume in 1 s) and/or induced naso-ocular symptoms.