Table 1 Variable region heavy chain genes identified from spleen tissue
From: The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus
GC/cluster | VH gene | DH gene | JH gene | Number of sequences isolated |
|---|---|---|---|---|
A | VH2–5*02 | 3–10*01 | 5*02 | 1 |
VH3–15*01 | 2–21*02 | 4*02 | 3 | |
VH3–23*01 | 1–26*01 | 5*02 | 3 | |
VH3–30*03 | 3–22*01 | 4*02 | 1 | |
VH3–43*02 | 1 | |||
VH3–74*02 | 2–15*01 | 6*02 | 2 | |
VH5–51 | 3–10 | 4*02 | 4 | |
B | VH2–5*02 | 1–26*01 | 5*01 | 3 |
VH3–21*01 | 2 | |||
VH3–30*03 | 2–8*01 | 6*02 | 1 | |
VH3–30*03 | 2–8*01 | 4*02 | 1 | |
VH3–30.3*01 | 3–3*01 | 6*02 | 8 | |
VH4–30.1 | 2–2*01 | 4*02 | 1 | |
C | VH2–5*02 | 5*02 | 2(1) | |
VH3–15*01 | 1 | |||
VH3–21*01 | 1 | |||
VH3–23*01 | 2*01 | 1 | ||
VH3–23*01 | 3–10*02 | 6*03 | 9 | |
VH3–30*03 | 3*02 | 1 | ||
VH3–30*03 | 2 | |||
VH3–33*01 | 5–24*01 | 3*02 | 1 | |
VH3–74*01 | (1) | |||
VH4–4*03 | 4*02 | 1 | ||
VH4–30.4*01 | 2–2*01 | 6*02 | 5(3) | |
VH4–34*01 | 5*02 | 1 | ||
VH4–59 | 1–26*01 | 4*02 | 1 | |
VH5–51*01 | 2–2*01 | 4*02 | 11 | |
VH5–51*01 | 2–2*01 | 4*02 | 3(1) | |
VH5–51*01 | 4–4*01 | 3*02 | 2 | |
D | VH3–07 | 2–15 | 3*02 | 13(10) |
VH3–23 | 3–22 | 6*03 | 3(1) | |
VH3–33 | 6–13*01 | 4*02 | 2 | |
VH3–72*01 | 5–5*01 | 4*02 | 1 | |
VH4–59*02 | 5–24*01 | 4*02 | 1 | |
VH5–51*01 | 2–2*01 | 1*01 | 3(2) | |
VH5–51*01 | 6–13*01 | 4*02 | 1 |