From: The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus
Location | |||
---|---|---|---|
GC/cluster | Total VH Segment | Framework | CDR1and CDR2 |
A | |||
R/S ratio of all sequences | 3.11 | 7.6 | 2.9 |
Clone VH5–51 | 2.5 | 5 | 1.4 |
Clone VH3–15 | 2 | 2 | 1 |
Clone VH3–23 | 2 | 1:0 | 1:0 |
R/S of all clones | 2.75 | 5 | 1.4 |
B | |||
R/S ratio of all sequences | 3.6 | 2.6 | 8.1 |
Clone VH2–5 | 4.7 | 4:0 | 4.5 |
Clone VH3–3.30 | 2.8 | 1.5 | 12 |
R/S of all clones | 3 | 1.7 | 9 |
C | |||
R/S ratio of all sequences | 2.9 | 3 | 3.2 |
VH5–51–JH4 | 4.5 | 8 | 1 |
VH3–23 | 2.7 | 2.4 | 4 |
VH5–51–D2–2 | 23.5 | 22 | 3:0 |
VH4–30 | 3 | 2 | 6 |
R/S of all clones | 6 | 6.4 | 4.6 |
D | |||
R/S ratio of all sequences | 2. 9 | 2.9 | 2.9 |
VH3–07 | 2.4 | 1.7 | 7 |
VH3–23 | 4.5 | 3.5 | 2:0 |
VH5–51 | 2.75 | 2 | 3:0 |
R/S of all clones | 2.8 | 2.1 | 12 |