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Table 1 Overall sensitivity and specificity of anti-centromere antibodies by indirect immunofluorescence in diagnosis of SSc

From: The clinical relevance of autoantibodies in scleroderma

SSc versus:

Sensitivity (%)

Specificity (%)

Normal controls

33* †

99.9* †

Other connective tissue diseases

31*

95†-97*

Primary Raynaud's phenomenon

24*

90*

Non-SSc relatives

19*

>99†*

  1. *Reference [35]. †Reference [36].