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Table 2 Overall sensitivity and specificity of anti-centromere antibodies by indirect immunofluorescence in diagnosis of CREST [40]

From: The clinical relevance of autoantibodies in scleroderma

CREST versus: Sensitivity (%) Specificity (%)
Normal controls 65 99.9
Other connective tissue diseases 61 98
Primary Raynaud's phenomenon 60 83
SSc 61 84