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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis

Figure 3

Analyses of paired samples of blood (B) and synovial tissue (ST) Bcells from the same rheumatoid arthritis patient. Results using both thegenomic DNA-based assay and the complementary (c)DNA-based assay for the threemajor immunoglobulin isotypes (M, G, and A) are shown. Certain clones arerestricted to the blood (â–¶), others to the joint (â–·), and others are commonto both compartments (â—†).

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