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Table 2 Effects of mast cell activation on cytokine production by explanted rheumatoid synovial tissue

From: Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion

 

Tryptase

TNF-α

IL-β

IL-15

Sample

Control

Anti-IgE

Control

Anti-IgE

Control

Anti-IgE

Control

Anti-IgE

753

11.1

30.4

138

6.4

24.2

4.1

0.31

0.28

764

28.1

181.6

271

204

11.4

20.9

0.55

0.4

770

8.6

46.6

12.8

276

30.3

11.9

0.54

0.54

773

8.9

47.9

103

8.5

19.1

5.8

0.27

0.3

798

32.3

42.1

97.8

34.6

165.3

38

0.52

0.49

Averaged values

17.8

69.7

177.2

53.2

50.1

16.1

0.44

0.40

  1. Values expressed as ng/ml per 100 mg tissue per 20 h for tryptaseand as pg/ml per 100 mg tissue for cytokines. For tryptase P = 0.05,for tumour necrosis factor-α P = 0.02, and for interleukin(IL)-1β P = 0.28, by Student's T-test. Ig,immunoglobulin.
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Arthritis Research & Therapy

ISSN: 1478-6362

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