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Table 2 Effects of mast cell activation on cytokine production by explanted rheumatoid synovial tissue

From: Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion

  Tryptase TNF-α IL-β IL-15
Sample Control Anti-IgE Control Anti-IgE Control Anti-IgE Control Anti-IgE
753 11.1 30.4 138 6.4 24.2 4.1 0.31 0.28
764 28.1 181.6 271 204 11.4 20.9 0.55 0.4
770 8.6 46.6 12.8 276 30.3 11.9 0.54 0.54
773 8.9 47.9 103 8.5 19.1 5.8 0.27 0.3
798 32.3 42.1 97.8 34.6 165.3 38 0.52 0.49
Averaged values 17.8 69.7 177.2 53.2 50.1 16.1 0.44 0.40
  1. Values expressed as ng/ml per 100 mg tissue per 20 h for tryptaseand as pg/ml per 100 mg tissue for cytokines. For tryptase P = 0.05,for tumour necrosis factor-α P = 0.02, and for interleukin(IL)-1β P = 0.28, by Student's T-test. Ig,immunoglobulin.