Table 2 Percentage of synovial cells expressing HIF-1α and HIF-2α proteins in normal, rheumatoid, and osteoarthritic synovium
From: Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis
Normal (n= 22) | OA (n = 34) | RA (n = 22) | ||||
|---|---|---|---|---|---|---|
HIF-1α | HIF-2α | HIF-1α | HIF-2α | HIF-1α | HIF-2α | |
Minimum | 0.00 | 0.00 | 20.00 | 0.00 | 10.00 | 10.00 |
25th percentile | 0.00 | 0.00 | 40.00 | 30.00 | 35.00 | 25.00 |
Median | 0.00 | 0.00 | 60.00 | 50.00 | 50.00 | 60.00 |
75th percentile | 10.00 | 0.00 | 90.00 | 90.00 | 75.00 | 80.00 |
Maximum | 20.00 | 10.00 | 100.0 | 100.0 | 80.00 | 80.00 |
Mean | 5.45 | 1.81 | 63.53 | 55.29 | 50.91 | 50.91 |
Standard deviation | 9.11 | 3.94 | 29.12 | 32.50 | 24.08 | 28.10 |
Standard error | 1.94 | 0.84 | 4.99 | 5.57 | 5.13 | 5.99 |
Lower 95% CI | 1.41 | 0.06 | 53.37 | 43.96 | 40.23 | 39.55 |
Upper 95% CI | 9.49 | 3.56 | 73.69 | 66.63 | 61.59 | 63.37 |