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Table 3 Expression of HIF-1α and HIF-2α in normal, rheumatoid, and osteoarthritic synovium

From: Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis

 

Fractures

RA

OA

P

HIF-1α

    

   Negative

16

0

0

 

   Low

6

10

13

<0.0001

   High

0

12

21

 

HIF-2α

    

   Negative

18

0

0

 

   Low

4

8

14

<0.0001

   High

0

14

20

 
  1. HIF, hypoxia inducible factor; OA, osteoarthritis; RA, rheumatoid arthritis.