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Table 3 Expression of HIF-1α and HIF-2α in normal, rheumatoid, and osteoarthritic synovium

From: Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis

  Fractures RA OA P
HIF-1α     
   Negative 16 0 0  
   Low 6 10 13 <0.0001
   High 0 12 21  
HIF-2α     
   Negative 18 0 0  
   Low 4 8 14 <0.0001
   High 0 14 20  
  1. HIF, hypoxia inducible factor; OA, osteoarthritis; RA, rheumatoid arthritis.