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Table 3 Spearman rank correlations between baseline laboratory test findings in postmenopausal women with rheumatoid arthritis

From: Hormone replacement therapy in rheumatoid arthritis is associated with lower serum levels of soluble IL-6 receptor and higher insulin-like growth factor 1

Test TNF-α IL-1Ra IL-6 sIL-6R IGF-1 ESR Estradiol
Serum TNF-α (pg/ml) 0.259* 0.041 0.346** -0.128 0.135 -0.042
Serum IL-1Ra (pg/ml) 0.259* 0.338** 0.434*** -0.021 0.108 0.088
Serum IL-6 (pg/ml) 0.041 0.338** 0.261* -0.245* 0.470*** 0.116
Serum sIL-6R (pg/ml) 0.346** 0.434*** 0.261* -0.207 0.115 0.145
Serum IGF-1 (ng/ml) -0.128 -0.021 -0.245* -0.207 -0.177 0.014
ESR (mm) 0.135 0.108 0.470*** 0.115 -0.177 0.015
Serum estradiol (pmol/l) -0.042 0.088 0.116 0.145 0.014 0.015
  1. *P < 0.05, **P < 0.01, ***P < 0.001. ESR = erythrocyte sedimentation rate; IGF-1 = insulin-like growth factor 1; IL-1Ra = IL-1-receptor antagonist; sIL-6R = soluble IL-6 receptor; TNF-α = tumor necrosis factor α.