Figure 2From: Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6Combined effects of IL-17 (20 ng/ml) plus IL-1β (10 ng/ml) or IL-17 plus TNF-α (10 ng/ml) on the expression of IL-6 and IL-8. Fibroblast-like synoviocytes were cultured for 72 hours in the presence of cytokines, and the concentrations of IL-6 or IL-8 in supernatants were determined. Measurements were made on synoviocytes from four different patients. *P < 0.05 in comparison with the results of IL-17 stimulation.Back to article page