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Figure 6 | Arthritis Res Ther

Figure 6

From: Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6

Figure 6

Effects of protein kinase inhibitors on the expression of TSG-6 mRNA. Fibroblast-like synoviocytes were cultured for 24 hours with or without IL-17 (20 ng/ml) and the appropriate inhibitor. Total RNA (0.5 μg) was used for cDNA synthesis in a volume of 10 μl; 1.5 μl of the synthesized cDNA was used for real-time PCR as described. Results are given as a percentage of the basal control (culture without cytokine set at 100%). Results are from four different patients, each measured in duplicate. *P < 0.05 in comparison with the results of IL-17 stimulation.

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